Safety Data Sheet
Dow Chemical Company Ltd

Dow Chemical Company Ltd

 encourages and expects you to read and understand the entire (M)SDS, as there is important information throughout the document.  We expect you to follow the precautions identified in this document unless your use conditions would necessitate other appropriate methods or actions.
1.	Identification of the substance/preparation and of the company/undertaking
Product Name
BETAWIPE (TM) 4001

Use of the substance/preparation 
An activator --  For use in automotive applications.  

Company Identification
Dow Chemical Company Ltd
2 Heathrow Blvd., 284 Bath Rd
UB7 0DQ  West Drayton, Middlesex, EN
United Kingdom

Customer Information Number:	0208-917-5000

Emergency Telephone Number24-Hour Emergency Contact:	+44 (0) 1553 761 251	Local Emergency Contact:00 44 155 37 61 251

2.	Composition/information on ingredients

Component	AmountClassification:CAS # 	EC #
Diphenylmethane-4,4'-diisocyanate (MDI), isomers(1) and homologues(2), blending of (1) and (2)	> 1.0 - < 5.0 %Xn: R20, R36/37/38, R42/43	9016-87-9	Not applicable
Ethyl acetate	> 20.0 - < 25.0 %F: R11; Xi: R36; R66; R67	141-78-6	205-500-4
Toluene	< 5.0 %F: R11; Repr.Cat.3: R63; Xn: R48/20, R65; Xi: R38; R67	108-88-3	203-625-9
4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate (MDI)	> 1.0 - < 5.0 %Xn: R20; Xi: R36/37/38; R42/43	101-68-8	202-966-0
Dibutyltin dilaurate	> 0.25 - < 1.0 %N: R50/53; Xn: R22, R48/22; R36/38	77-58-7	201-039-8
Butanone; ethyl methyl ketone	> 55.0 - < 65.0 %F: R11; Xi: R36; R66; R67	78-93-3	201-159-0
	
See Section 16 for full text of R-phrases.

3.	Hazards Identification

Highly flammable.
Vapours may cause drowsiness and dizziness.
Irritating to eyes, respiratory system and skin.
May cause sensitization by inhalation and skin contact.
Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

4.	First-aid measures

Eye Contact: Immediately flush eyes with water; remove contact lenses, if present, after the first 5 minutes, then continue flushing eyes for at least 15 minutes. Obtain medical attention without delay, preferably from an ophthalmologist.  
Skin Contact: Remove material from skin immediately by washing with soap and plenty of water.  Remove contaminated clothing and shoes while washing.  Seek medical attention if irritation persists. Wash clothing before reuse.  An MDI skin decontamination study demonstrated that cleaning very soon after exposure is important, and that a polyglycol-based skin cleanser or corn oil may be more effective than soap and water.  Discard items which cannot be decontaminated, including leather articles such as shoes, belts and watchbands.  
Inhalation: Move person to fresh air.  If not breathing, give artificial respiration; if by mouth to mouth use rescuer protection (pocket mask, etc).  If breathing is difficult,  oxygen should be administered by qualified personnel.  Call a physician or transport to a medical facility.  
Ingestion: Do not induce vomiting. Call a physician and/or transport to emergency facility immediately.  
Notes to Physician: If lavage is performed, suggest endotracheal and/or esophageal control.  Danger from lung aspiration must be weighed against toxicity when considering emptying the stomach.  The decision of whether to induce vomiting or not should be made by a physician.  May cause respiratory sensitization or asthma-like symptoms.  Bronchodilators, expectorants and antitussives may be of help.  Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids.  Respiratory symptoms, including pulmonary edema, may be delayed. Persons receiving significant exposure should be observed 24-48 hours for signs of respiratory distress.  Maintain adequate ventilation and oxygenation of the patient.  If you are sensitized to diisocyanates, consult your physician regarding working with other respiratory irritants or sensitizers.  No specific antidote.  Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient.  
Medical Conditions Aggravated by Exposure: Excessive exposure may aggravate preexisting asthma and other respiratory disorders (e.g. emphysema, bronchitis, reactive airways dysfunction syndrome).  Skin contact may aggravate preexisting dermatitis.  

5.	Fire Fighting Measures

Extinguishing Media: Carbon dioxide fire extinguishers.  Dry chemical fire extinguishers.  Foam.  
Extinguishing Media to Avoid: Do not use direct water stream.  
Fire Fighting Procedures: Keep people away.  Isolate fire and deny unnecessary entry.  
Special Protective Equipment for Firefighters: Wear positive-pressure self-contained breathing apparatus (SCBA) and protective fire fighting clothing (includes fire fighting helmet, coat, trousers, boots, and gloves).  
Unusual Fire and Explosion Hazards: Vapors are heavier than air and may travel a long distance and accumulate in low lying areas. Ignition and/or flash back may occur.  Extremely flammable.  
Hazardous Combustion Products: Carbon monoxide is highly toxic if inhaled; carbon dioxide in sufficient concentrations can act as an asphyxiant.  
6.	Accidental Release Measures
Steps to be Taken if Material is Released or Spilled: Contain spilled material if possible.  Absorb with materials such as:  Cat litter.  Sand.  Sawdust.  Use non-sparking tools in cleanup operations.  Recover if possible, or dispose of according to applicable regulations.  See Section 13, Disposal Considerations, for additional information.  
Personal Precautions: Evacuate area.  Eliminate all sources of ignition in vicinity of spill or released vapor to avoid fire or explosion.  Ground and bond all containers and handling equipment.  Wear suitable protective equipment.  Use appropriate safety equipment. For additional information, refer to Section 8, Exposure Controls and Personal Protection.  Ventilate area of leak or spill.  
Environmental Precautions: Dike to prevent contamination of ground and surface water, then transfer into closed containers.  

7.	Handling and Storage

Handling 
General Handling: No smoking, open flames or sources of ignition in handling and storage area.  Electrically ground and bond all equipment.  Use of non-sparking or explosion-proof equipment may be necessary, depending upon the type of operation.  Containers, even those that have been emptied, can contain vapors. Do not cut, drill, grind, weld, or perform similar operations on or near empty containers.  Never use air pressure for transferring product.  

Storage 
Store in a cool, dry place.  
 	Storage temperature: 	 	
	5 - 35 °C		

8.	Exposure Controls / Personal Protection
Exposure Limits
Component 	List	Type 	Value 	
| 4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate (MDI)	Ireland OELV	TWA  as NCO	0.02 mg/m3   SEN  	
	Ireland OELV	STEL  as NCO	0.07 mg/m3   SEN  	
	ACGIH	TWA  	0.005 ppm     	
	UK WEL	TWA  as NCO	0.02 mg/m3   SEN  	
	UK WEL	STEL  as NCO	0.07 mg/m3   SEN  	
 4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate (MDI)	UK WEL	HAZ_DES	Respiratory irritant. 	
| Butanone; ethyl methyl ketone	Ireland OELV	TWA  	600 mg/m3  200 ppm   SKIN  	
	Ireland OELV	STEL  	900 mg/m3  300 ppm   SKIN  	
	ACGIH	TWA  	200 ppm   BEI  	
	ACGIH	STEL  	300 ppm   BEI  	
	EU IOELV	TWA  	600 mg/m3  200 ppm     	
	EU IOELV	STEL  	900 mg/m3  300 ppm     	
	UK WEL	TWA  	600 mg/m3  200 ppm   SKIN  	
	UK WEL	STEL  	899 mg/m3  300 ppm   SKIN  	
| Toluene	Ireland OELV	TWA  	188 mg/m3  50 ppm   SKIN  	
	Ireland OELV	STEL  	560 mg/m3  150 ppm   SKIN  	
	ACGIH	TWA  	50 ppm   SKIN, BEI  	
	UK WEL	TWA  	191 mg/m3  50 ppm   SKIN  	
	UK WEL	STEL  	574 mg/m3  150 ppm   SKIN  	
| Ethyl acetate	Ireland OELV	TWA  	1,400 mg/m3  400 ppm     	
	ACGIH	TWA  	400 ppm     	
	UK WEL	TWA  	200 ppm     	
	UK WEL	STEL  	400 ppm     	
|
A "skin" notation following the exposure guideline refers to the potential for dermal absorption of the material including mucous membranes and the eyes either by contact with vapors or by direct skin contact.
It is intended to alert the reader that inhalation may not be the only route of exposure and that measures to minimize dermal exposures should be considered.
A BEI notation following the exposure guideline refers to a guidance value for assessing biological monitoring results as an indicator of the uptake of a substance from all routes of exposures.
A "SEN" notation following the exposure guideline refers to the potential to produce sensitization, as confirmed by human or animal data.

Personal Protection
Eye/Face Protection: 
Skin Protection: Use protective clothing chemically resistant to this material.  Selection of specific items such as face shield, boots, apron, or full body suit will depend on the task.  Remove contaminated clothing immediately, wash skin area with soap and water, and launder clothing before reuse or dispose of properly.  Items which cannot be decontaminated, such as shoes, belts and watchbands, should be removed and disposed of properly.  
Respiratory Protection: Atmospheric levels should be maintained below the exposure guideline. When atmospheric levels may exceed the exposure guideline, use an approved air-purifying respirator equipped with an organic vapor sorbent and a particle filter.  For situations where the atmospheric levels may exceed the level for which an air-purifying respirator is effective, use a positive-pressure air-supplying respirator (air line or self-contained breathing apparatus).  For emergency response or for situations where the atmospheric level is unknown, use an approved positive-pressure self-contained breathing apparatus or positive-pressure air line with auxiliary self-contained air supply.  Use the following CE approved air-purifying respirator:  Organic vapor cartridge with a particulate pre-filter, type AP2.  
Ingestion: Avoid ingestion of even very small amounts; do not consume or store food or tobacco in the work area; wash hands and face before smoking or eating.  

Engineering Controls
Ventilation: Use only with adequate ventilation.  Local exhaust ventilation may be necessary for some operations.  Provide general and/or local exhaust ventilation to control airborne levels below the exposure guidelines.  Exhaust systems should be designed to move the air away from the source of vapor/aerosol generation and people working at this point.  The odor and irritancy of this material are inadequate to warn of excessive exposure.  
9.	Physical and Chemical Properties

Physical StateLiquid	
Color	Colorless to yellow	
Odor	Characteristic	
Flash Point - Closed Cup	-6 °C Closed Cup 	
Flammable Limits In Air	Lower: No test data available  	
Upper: No test data available 	
Autoignition TemperatureNo test data available 	
Vapor PressureNo test data available	
Boiling Point (760 mmHg)No test data available.   	
Vapor Density (air = 1)No test data available	
Specific Gravity (H2O = 1)0.87 Vendor 	
Freezing PointNo test data available	
Melting PointNo test data available	
Solubility in Water (by weight)No test data availablepHNo test data available	
Molecular WeightNo test data available	Percent Volatiles 	No test data available	
Dynamic Viscosity	No test data available	
Particle Size 	No test data available	
Saturated Vapor Concentration 	No test data available	

10.	Stability and Reactivity

Stability/Instability
Stable under recommended storage conditions.  See Storage, Section 7.  
Conditions to Avoid: Some components of this product can decompose at elevated temperatures.  

Incompatible Materials: Strong oxidizers.  Acids.  
Hazardous Decomposition Products: Decomposition products depend upon temperature, air supply and the presence of other materials.  

Hazardous Polymerization
Will not occur.  

11.	Toxicological Information
Acute Toxicity
Ingestion
Low toxicity if swallowed.  Small amounts swallowed incidentally as a result of normal handling operations are not likely to cause injury; however, swallowing larger amounts may cause injury.  Swallowing may result in gastrointestinal irritation.  Aspiration into the lungs may occur during ingestion or vomiting, causing lung damage or even death due to chemical pneumonia.  
Single dose oral LD50 has not been determined.  
Eye Contact
May cause moderate eye irritation.  May cause moderate corneal injury.  Vapor may cause lacrimation (tears).  Vapor may cause eye irritation experienced as mild discomfort and redness.  
Skin Contact
Prolonged contact may cause moderate skin irritation with local redness.  May cause drying and flaking of the skin.  May stain skin.  
Skin Absorption
Prolonged skin contact is unlikely to result in absorption of harmful amounts.  
Inhalation
Vapor concentrations are attainable which could be hazardous on single exposure.  May cause respiratory irritation and central nervous system depression.  Symptoms may include headache, dizziness and drowsiness, progressing to incoordination and unconsciousness.  May cause nausea and vomiting.  Alcohol consumption and exertion may increase the adverse effects of toluene.  Decreased lung function has been associated with overexposure to isocyanates.  For the minor component(s):  May cause pulmonary edema (fluid in the lungs.)  
Sensitization
Skin
Skin contact may cause an allergic skin reaction.  Animal studies have shown that skin contact with isocyanates may play a role in respiratory sensitization.    
Respiratory
For the minor component(s):  May cause allergic respiratory response.  MDI concentrations below the exposure guidelines may cause allergic respiratory reactions in individuals already sensitized.  Asthma-like symptoms may include coughing, difficult breathing and a feeling of tightness in the chest. Occasionally, breathing difficulties may be life threatening.    
Repeated Dose Toxicity
Contains component(s) which have been reported to cause effects on the following organs in animals:  Blood.  Liver.  Kidney.  Gastrointestinal tract.  Central nervous system.  Respiratory tract.  Methyl ethyl ketone is probably not neurotoxic in itself but it potentiates the neurotoxicity of methyl-n-butyl ketone and n-hexane.  Tissue injury in the upper respiratory tract and lungs has been observed in laboratory animals after repeated excessive exposures to MDI/polymeric MDI aerosols.  Toluene has caused hearing loss in laboratory animals upon exposure to high concentrations.  Intentional misuse by deliberately inhaling toluene may cause nervous system damage, hearing loss, liver and kidney effects and death.    
Chronic Toxicity and Carcinogenicity 
Lung tumors have been observed in laboratory animals exposed to aerosol droplets of MDI/Polymeric MDI (6 mg/m3) for their lifetime.  Tumors occurred concurrently with respiratory irritation and lung injury.  Current exposure guidelines are expected to protect against these effects reported for MDI.    
Developmental Toxicity
In laboratory animals, toluene has been toxic to the fetus at doses toxic to the mother; it has caused birth defects in mice when administered orally, but not by inhalation.  In laboratory animals, MDI/polymeric MDI did not cause birth defects; other fetal effects occurred only at high doses which were toxic to the mother.  Contains component(s) which did not cause birth defects in animals; other fetal effects occurred only at doses toxic to the mother.  
Reproductive Toxicity
Contains component(s) which did not interfere with reproduction in animal studies.  
Genetic Toxicology 
The majority of the many genetic toxicity studies done on toluene and methyl ethyl ketone, both in vitro and in animals, have been negative.  Contains component(s) which were negative in some in vitro genetic toxicity studies and positive in others.  Genetic toxicity data on MDI are inconclusive. MDI was weakly positive in some in vitro studies; other in vitro studies were negative.  Animal mutagenicity studies were predominantly negative.    

12.	Ecological Information

Chemical Fate
Data for Component:  Diphenylmethane-4,4'-diisocyanate (MDI), isomers(1) and homologues(2), blending of (1) and (2)
Movement & Partitioning
In the aquatic and terrestrial environment, movement is expected to be limited by its reaction with water forming predominantly insoluble polyureas.  

Persistence and Degradability
In the aquatic and terrestrial environment, material reacts with water forming predominantly insoluble polyureas which appear to be stable.  In the atmospheric environment, material is expected to have a short tropospheric half-life, based on calculations and by analogy with related diisocyanates.  

Data for Component:  Ethyl acetate
Movement & Partitioning
Bioconcentration potential is low (BCF less than 100 or log Pow less than 3).  Potential for mobility in soil is very high (Koc between 0 and 50).  
Henry's Law Constant (H): 1.2E-4 atm*m3/mole; 25 °C  Measured
Partition coefficient, n-octanol/water (log Pow): 0.73  Measured
Partition coefficient, soil organic carbon/water (Koc): 3  Estimated
Bioconcentration Factor (BCF): 30; fish; Measured

Persistence and Degradability
Material is readily biodegradable.  Passes OECD test(s) for ready biodegradability.  
OECD Biodegradation Tests:  
Biodegradation	Exposure Time	Method	100 %	28 d	OECD 301D Test	
Data for Component:  Toluene
Movement & Partitioning
Bioconcentration potential is low (BCF less than 100 or log Pow less than 3).  Potential for mobility in soil is very high (Koc between 0 and 50).  
Henry's Law Constant (H): 6.46E-03 atm*m3/mole; 25 °C  Estimated
Partition coefficient, n-octanol/water (log Pow): 2.73  Measured
Partition coefficient, soil organic carbon/water (Koc): 37 - 178  Estimated
Bioconcentration Factor (BCF): 13.2 - 90; fish; Measured

Persistence and Degradability
Material is readily biodegradable.  Passes OECD test(s) for ready biodegradability.  
OECD Biodegradation Tests:  
Biodegradation	Exposure Time	Method	100 %	14 d	OECD 301C Test	
Data for Component:  4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate (MDI)
Movement & Partitioning
In the aquatic and terrestrial environment, movement is expected to be limited by its reaction with water forming predominantly insoluble polyureas.  

Persistence and Degradability
In the aquatic and terrestrial environment, material reacts with water forming predominantly insoluble polyureas which appear to be stable.  In the atmospheric environment, material is expected to have a short tropospheric half-life, based on calculations and by analogy with related diisocyanates.  

Data for Component:  Dibutyltin dilaurate
Movement & Partitioning
Bioconcentration potential is moderate (BCF between 100 and 3000 or Log Pow between 3 and 5).  Potential for mobility in soil is low (Koc between 500 and 2000).  
Partition coefficient, n-octanol/water (log Pow): 3.12  Measured
Partition coefficient, soil organic carbon/water (Koc): 1,187  Measured
Bioconcentration Factor (BCF): 120; common carp (Cyprinus carpio); Measured

Data for Component:  Butanone; ethyl methyl ketone
Movement & Partitioning
Bioconcentration potential is low (BCF less than 100 or log Pow less than 3).  Potential for mobility in soil is very high (Koc between 0 and 50).  
Henry's Law Constant (H): 2.44E-5 atm*m3/mole; 25 °C  Measured
Partition coefficient, n-octanol/water (log Pow): 0.29  Measured
Partition coefficient, soil organic carbon/water (Koc): 3.8  Estimated

Persistence and Degradability
Material is expected to be readily biodegradable.  

Ecotoxicity
Data for Component: Diphenylmethane-4,4'-diisocyanate (MDI), isomers(1) and homologues(2), blending of (1) and (2)
The measured ecotoxicity is that of the hydrolyzed product, generally under conditions maximizing production of soluble species.  Material is not classified as dangerous to aquatic organisms (LC50/EC50/IC50 greater than 100 mg/L in most sensitive species).  

Toxicity to Soil Dwelling Organisms
LC50, Earthworm Eisenia foetida, adult, 14 d: > 1,000 mg/kg
Data for Component: Ethyl acetate
Material is not classified as dangerous to aquatic organisms (LC50/EC50/IC50 greater than 100 mg/L in most sensitive species).  

Fish Acute & Prolonged Toxicity
LC50, fathead minnow (Pimephales promelas): 230 - 290 mg/l
LC50, guppy (Poecilia reticulata): 210 mg/l
Aquatic Invertebrate Acute Toxicity
EC50, water flea Daphnia pulex, immobilization: 262 mg/l
Aquatic Plant Toxicity
EC50, green alga Selenastrum capricornutum, biomass growth inhibition: > 2,000 mg/l
Data for Component: Toluene
Material is toxic to aquatic organisms (LC50/EC50/IC50 between 1 and 10 mg/L in most sensitive species).  

Fish Acute & Prolonged Toxicity
LC50, bluegill (Lepomis macrochirus): 12.7 - 340 mg/l
Aquatic Invertebrate Acute Toxicity
LC50, water flea Daphnia magna: 60 - 313 mg/l
LC50, bay shrimp Crangon franciscorum: 3.7 mg/l
Aquatic Plant Toxicity
EC50, green alga Selenastrum capricornutum, biomass growth inhibition: > 433 mg/l
Toxicity to Micro-organisms
IC50; bacteria, Growth inhibition, 16 h: 29 mg/l
Toxicity to Soil Dwelling Organisms
LC50, Earthworm Eisenia foetida, adult: 150 - 280 mg/kg
Data for Component: 4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate (MDI)
The measured ecotoxicity is that of the hydrolyzed product, generally under conditions maximizing production of soluble species.  Material is not classified as dangerous to aquatic organisms (LC50/EC50/IC50 greater than 100 mg/L in most sensitive species).  

Toxicity to Soil Dwelling Organisms
LC50, Earthworm Eisenia foetida, adult, 14 d: > 1,000 mg/kg
Data for Component: Dibutyltin dilaurate
Material is considered very toxic to aquatic organisms (LC50/EC50/IC50 below 1 mg/L in most sensitive species).  

Fish Acute & Prolonged Toxicity
LC50, golden orfe (Leuciscus idus), 48 h: 2 mg/l
Aquatic Invertebrate Acute Toxicity
EC50, water flea Daphnia magna, 24 h, immobilization: 0.66 mg/l
Data for Component: Butanone; ethyl methyl ketone
Material is not classified as dangerous to aquatic organisms (LC50/EC50/IC50 greater than 100 mg/L in most sensitive species).  

Fish Acute & Prolonged Toxicity
LC50, bluegill (Lepomis macrochirus): 1,690 mg/l
Aquatic Invertebrate Acute Toxicity
EC50, water flea Daphnia magna, immobilization: 5,091 mg/l
Aquatic Plant Toxicity
EC50, alga Scenedesmus sp., biomass growth inhibition: 4,300 mg/l
Toxicity to Micro-organisms
EC50; bacteria, Growth inhibition (cell density reduction): > 1,000 mg/l
13.	Disposal Considerations

All disposal methods must be in compliance with the EU framework Directives 91/156/EEC, 91/689/EEC and their subsequent adaptations, as implemented in National Laws and Regulations, as well as EU Directives dealing with priority waste streams.  Transboundary shipment of wastes must be in compliance with EU Regulation 259/93 and subsequent modifications.  
Treatment and disposal methods of used packaging: Empty containers should be recycled or otherwise disposed of by an approved waste management facility.  CONTAMINATED PACKAGING:  Any disposal of contaminated packaging and washings must be in accordance with State, Territory and/or Local government regulations.  After container has been cleaned and labelling has been removed, empty containers can be sent for recycling or disposal.  If the container is to be reconditioned, the reconditioning company should be made aware of the nature of the original contents.  

14.	Transport Information
Road & Rail 
Proper Shipping Name: COATING SOLUTION
Hazard Class: 3   ID Number: UN1139   Packing Group: PG II

Classification: F1
Kemler Code: 33
Tremcard Number: 30GF1-I+II
Special prov. 640D / Special prov. 640D
Ocean
Proper Shipping Name: COATING SOLUTION
Hazard Class: 3   ID Number: UN1139   Packing Group: PG II
EMS Number: F-E,S-E 
Marine pollutant.: No

Air
Proper Shipping Name: COATING SOLUTION
Hazard Class: 3   ID Number: UN1139   Packing Group: PG II
Cargo Packing Instruction: 307
Passenger Packing Instruction: 305

Inland Waterways
Proper Shipping Name: COATING SOLUTION
Hazard Class: 3   ID Number: UN1139   Packing Group: PG II
Classification: F1
Kemler Code: 33
Tremcard Number: 30GF1-I+II
Special prov. 640D / Special prov. 640D

15.	Regulatory Information

European Inventory of Existing Commercial Chemical Substances (EINECS)
The components of this product are on the EINECS inventory or are exempt from inventory requirements.
US. Toxic Substances Control Act
All components of this product are either on the TSCA Inventory, are exempt from TSCA Inventory Requirements under 40 CFR 720.30, or comply with the PMN Polymer Exemption 40 CFR 723.250.
CEPA - Domestic Substances List (DSL)
All substances contained in this product are listed on the Canadian Domestic Substances List (DSL) or are not required to be listed.

EC Classification and User Label Information
Hazard Symbol :
F	-	Highly flammable.	
Xn	-	Harmful.	
Risk Phrases :
R11 - Highly flammable.
R67 - Vapours may cause drowsiness and dizziness.
R36/37/38 - Irritating to eyes, respiratory system and skin.
R42/43 - May cause sensitization by inhalation and skin contact.
R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

Safety Phrases :
S16 - Keep away from sources of ignition - no smoking.
S23 - Do not breathe vapour/gas/fumes/spray.
S24 - Avoid contact with skin.
S37 - Wear suitable gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
S61 - Avoid release to the environment. Refer to special instructions/Safety data sheets.
Contains:Diphenylmethane-4,4'-diisocyanate (MDI), isomers(1) and homologues(2), blending of (1) and (2)
4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate (MDI)
Contains isocyanates. See information supplied by the manufacturer.

16.	Other Information
Risk-phrases in Section 2
R11	Highly flammable.	R20	Harmful by inhalation.	R36	Irritating to eyes.	R36/37/38	Irritating to eyes, respiratory system and skin.	R36/38	Irritating to eyes and skin.	R38	Irritating to skin.	R42/43	May cause sensitization by inhalation and skin contact.	R48/20	Harmful: danger of serious damage to health by prolonged exposure through inhalation.	R48/22	Harmful: danger of serious damage to health by prolonged exposure if swallowed.	R50/53	Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.	R63	Possible risk of harm to the unborn child.	R65	Harmful: May cause lung damage if swallowed.	R66	Repeated exposure may cause skin dryness or cracking.	R67	Vapours may cause drowsiness and dizziness.	

Revision 
Identification Number: 83508 / 3005 / Issue Date 2006/07/03 / Version: 4.0
Most recent revision(s) are noted by the bold, double bars in left-hand margin throughout this document. 

Dow Chemical Company Ltd  urges each customer or recipient of this (M)SDS to study it carefully and consult appropriate expertise, as necessary or appropriate, to become aware of and understand the data contained in this (M)SDS and any hazards associated with the product.  The information herein is provided in good faith and believed to be accurate as of the effective date shown above.  However, no warranty, express or implied, is given.   Regulatory requirements are subject to change and may differ between various locations. It is the buyer's/user's responsibility to ensure that his activities comply with all federal, state, provincial or local laws.  The information presented here pertains only to the product as shipped.  Since conditions for use of the product are not under the control of the manufacturer, it is the buyer's/user's duty to determine the conditions necessary for the safe use of this product.   Due to the proliferation of sources for information such as manufacturer-specific (M)SDSs, we are not and cannot be responsible for (M)SDSs obtained from any source other than ourselves.  If you have obtained an (M)SDS from another source or if you are not sure that the (M)SDS you have is current, please contact us for the most current version.